The SILVEYRA Lab

At the Silveyra lab, we study how sex and hormones affect our lungs and their responses to environmental exposures. 

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With an interdisciplinary focus on physiology, endocrinology, and molecular immunology, our laboratory investigates mechanisms mediating sex differences in lung inflammation and lung disease.   

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We are currently investigating the following areas of research:

• Sex differences in lung inflammatory responses to environmental exposures (ambient ozone, particulate matter, allergens);

• The effects of the female reproductive cycle in lung inflammatory responses and asthma exacerbations;

• Circulating sex hormone's effects on pollution-induced lung inflammation; 

• Mechanisms of estrogen receptor regulation of lung inflammation;

• Sex differences in airway remodeling during asthma and ozone-induced asthma exacerbations.

• Sex differences in e-cigs and vaping exposure effects across the life span.

• The effects of environmental exposures such as endocrine disruptors in the lung's response to allergens and pollutants.

• The interplay of the lung and gut microbiomes in the context of lung health and disease.

• How diet and exercise affect the lung.